Why Should I Treat My Hepatitis C Now?

Important Safety Information | Important Facts

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WHY SHOULD I TREAT MY
HEPATITIS C NOW?

HEPATITIS C
AND
THE CONSEQUENCES

Hepatitis C is a contagious liver disease spread through contact with the blood of a person who has the virus. The disease progresses slowly, often showing no symptoms. That's why many of the 2.4 million Americans who have the disease don't even know it. And many don't know that it can be cured.

Cure means the hepatitis C virus is not detected in the blood when measured three months after treatment is completed.

If left untreated, hepatitis C can seriously damage your liver, which can eventually lead to death. In fact, hepatitis C kills more Americans than any other infectious disease reported to the Centers for Disease Control and Prevention.

Liver Damage Over Time

Healthy Liver - F0
Helps digest food. Breaks down harmful drugs and toxins.

A liver with early stage liver damage or mild fibrosis

Mild Fibrosis - F1
Minimal scarring in this early stage of liver damage.

A liver with moderate fibrosis, scar tissue continues to form

Moderate Fibrosis - F2
Scar tissue continues to form.

A liver with severe firbosis restricts blood flow

Severe Fibrosis - F3
Scar tissue begins to connect, restricting blood flow.

A liver with cirrhosis may not work as it should

Cirrhosis - F4
The liver may not work as it should due to the advanced scarring.

F0 F1 F2 F3 F4

Your Hepatitis C Specialist can determine a fibrosis score (F0 - F4) by blood test, ultrasound, or liver biopsy. Scores from these tests estimate the amount of scarring in the liver. The greater the fibrosis score, the more likely you are to have severe liver damage.

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Learn about a treatment option for hepatitis C

Talk to your Hepatitis C Specialist to find out if EPCLUSA could be your kind of cure for chronic hepatitis C. View cure rates across all 6 main hepatitis C genotypes.

Questions about insurance converage, savings, & support?

Cost shouldn't be a barrier to treatment: find out about the savings options available for EPCLUSA.

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FIND A HEPATITIS C
SPECIALIST:

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ELIGIBLE PEOPLE MAY PAY AS
LITTLE AS $5 PER CO-PAY.

Restrictions apply.

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Important Safety Information

What is the most important information I should know about EPCLUSA?

EPCLUSA can cause serious side effects, including:

Hepatitis B virus reactivation: Before starting EPCLUSA treatment, your healthcare provider will do blood tests to check for hepatitis B infection. If you have ever had hepatitis B, the hepatitis B virus could become active again during and after treatment with EPCLUSA. This may cause serious liver problems including liver failure and death. If you are at risk, your healthcare provider will monitor you during and after taking EPCLUSA.

Continued Below

Important Safety Information

What is the most important information I should know about EPCLUSA?

EPCLUSA can cause serious side effects, including:

Hepatitis B virus reactivation: Before starting EPCLUSA treatment, your healthcare provider will do blood tests to check for hepatitis B infection. If you have ever had hepatitis B, the hepatitis B virus could become active again during and after treatment with EPCLUSA. This may cause serious liver problems including liver failure and death. If you are at risk, your healthcare provider will monitor you during and after taking EPCLUSA.

What should I tell my healthcare provider before taking EPCLUSA?

Tell your healthcare provider about all of your medical conditions, including if you have ever had hepatitis B infection or liver problems other than hepatitis C infection; if you have severe kidney problems or are on dialysis; if you have HIV; or if you are pregnant or breastfeeding, or plan to become pregnant or breastfeed. It is not known if EPCLUSA will harm your unborn baby or pass into your breast milk. If you take EPCLUSA with ribavirin, you should also read the ribavirin Medication Guide for important pregnancy-related information.
Tell your healthcare provider and pharmacist about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. EPCLUSA and certain other medicines may affect each other, or may cause side effects.

What are the possible side effects of EPCLUSA?

Serious side effects may also include:

Slow heart rate (bradycardia): EPCLUSA, when taken with amiodarone (Cordarone^®, Nexterone^®, Pacerone^®), a medicine used to treat certain heart problems, may cause slow heart rate. In some cases slow heart rate has led to death or the need for a pacemaker when amiodarone is taken with medicines containing sofosbuvir. Get medical help right away if you take amiodarone with EPCLUSA and get any of the following symptoms: fainting or near-fainting, dizziness or lightheadedness, not feeling well, weakness, extreme tiredness, shortness of breath, chest pains, confusion, or memory problems.

The most common side effects of EPCLUSA include headache and tiredness. Tell your healthcare provider if you have any side effect that bothers you or does not go away.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

What is EPCLUSA?

EPCLUSA is a prescription medicine used to treat adults with chronic (lasting a long time) hepatitis C genotype 1, 2, 3, 4, 5, or 6 infection with or without cirrhosis (compensated). In those with advanced cirrhosis (decompensated), EPCLUSA is used with ribavirin.

Please see Important Facts about EPCLUSA including Important Warning.

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